Ertugliflozin L-pyroglutamic acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Ertugliflozin L-焦谷氨酸是一种选择性、口服活性的 hSGLT2 抑制剂，IC50 为 0.877 nM。

Ertugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-pyroglutamic acid can be used for studies about the treatment of type 2 diabetes mellitus.(In Vitro):Ertugliflozin L-pyroglutamic acid demonstrated >2000-fold selectivity for SGLT2 over SGLT.(In Vivo):The oral administration of Ertugliflozin L-pyroglutamic to rats acid showed concentration-dependent glucosuria.

——

——

PF-04971729 L-pyroglutamic acid

Others

Other Targets

Caspase-3

——

——

1210344-83-4

566

C27H32ClNO10

>98% (HPLC)

In Vitro:?DMSO : ≥ 125 mg/mL (220.85 mM)

OC(=O)[C@@H]1CCC(=O)N1.CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1

——

(-20℃)

With Ice Pack

≥ 2 years