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Ertugliflozin L-pyroglutamic acid
CAS No. 1210344-83-4
Ertugliflozin L-pyroglutamic acid ( PF-04971729 L-pyroglutamic acid )
产品货号. M26680 CAS No. 1210344-83-4
Ertugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥316 | 有现货 |
|
| 10MG | ￥446 | 有现货 |
|
| 25MG | ￥664 | 有现货 |
|
| 50MG | ￥786 | 有现货 |
|
| 100MG | ￥1158 | 有现货 |
|
| 200MG | ￥1693 | 有现货 |
|
| 500MG | ￥2900 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Ertugliflozin L-pyroglutamic acid
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Ertugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM.
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产品描述Ertugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-pyroglutamic acid can be used for studies about the treatment of type 2 diabetes mellitus.(In Vitro):Ertugliflozin L-pyroglutamic acid demonstrated >2000-fold selectivity for SGLT2 over SGLT.(In Vivo):The oral administration of Ertugliflozin L-pyroglutamic to rats acid showed concentration-dependent glucosuria.
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同义词PF-04971729 L-pyroglutamic acid
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通路Others
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靶点Other Targets
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受体Caspase-3
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研究领域——
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适应症——
化学信息
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CAS Number1210344-83-4
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分子量566.0
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分子式C27H32ClNO10
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纯度>98% (HPLC)
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溶解度——
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SMILESOC(=O)[C@@H]1CCC(=O)N1.CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Kravchenko DV, et al. Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. J Med Chem. 2005 Jun 2;48(11):3680-3.
产品手册
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